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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKX
All Species:
18.18
Human Site:
T343
Identified Species:
28.57
UniProt:
P51817
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51817
NP_005035.1
358
40896
T343
Y
P
E
N
D
W
D
T
A
A
P
V
P
Q
K
Chimpanzee
Pan troglodytes
XP_001145269
358
40936
T343
Y
P
E
N
D
W
D
T
A
A
P
V
P
Q
K
Rhesus Macaque
Macaca mulatta
XP_001086667
358
40973
T343
Y
P
E
N
D
W
D
T
A
A
P
V
P
Q
K
Dog
Lupus familis
XP_852513
341
38934
T326
Y
P
E
N
D
W
N
T
A
P
P
V
S
P
K
Cat
Felis silvestris
Mouse
Mus musculus
Q922R0
355
40448
K340
Y
P
E
S
E
L
D
K
T
P
S
V
S
D
K
Rat
Rattus norvegicus
P68182
351
40689
V338
Y
E
E
E
E
I
R
V
S
I
T
E
K
C
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514495
450
51108
K435
Y
P
E
D
D
W
N
K
T
P
P
V
P
P
K
Chicken
Gallus gallus
XP_416852
365
41407
K350
Y
P
E
D
D
W
N
K
M
P
P
V
P
P
K
Frog
Xenopus laevis
Q7ZX15
486
56292
T454
E
F
T
A
Q
S
I
T
L
T
P
P
D
R
Y
Zebra Danio
Brachydanio rerio
XP_690430
357
40786
K342
Y
P
D
E
E
W
K
K
D
T
P
V
P
A
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16912
583
65389
P568
Y
P
E
K
D
W
K
P
A
K
A
V
D
Q
R
Honey Bee
Apis mellifera
XP_393711
374
42855
S359
Y
P
E
T
D
W
R
S
Q
P
P
L
P
P
E
Nematode Worm
Caenorhab. elegans
P21137
404
46327
F389
E
V
Q
E
P
T
E
F
V
I
A
A
T
P
Q
Sea Urchin
Strong. purpuratus
XP_001199876
248
28648
D240
D
A
S
P
V
K
S
D
V
L
K
L
F
K
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P06244
397
46057
Y382
Y
P
E
E
D
I
N
Y
G
V
Q
G
E
D
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93
98
80.1
N.A.
77.3
49.1
N.A.
66
81.3
31.6
73.7
N.A.
38.4
56.6
42
47.7
Protein Similarity:
100
95.5
98.3
85.4
N.A.
84.9
68.4
N.A.
72
87.9
46.2
84.3
N.A.
49.9
72.1
61.1
58.6
P-Site Identity:
100
100
100
73.3
N.A.
40
13.3
N.A.
60
60
13.3
46.6
N.A.
53.3
46.6
0
0
P-Site Similarity:
100
100
100
80
N.A.
53.3
26.6
N.A.
73.3
73.3
20
60
N.A.
60
66.6
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
43
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
62.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
7
0
0
0
0
34
20
14
7
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% C
% Asp:
7
0
7
14
60
0
27
7
7
0
0
0
14
14
7
% D
% Glu:
14
7
74
27
20
0
7
0
0
0
0
7
7
0
7
% E
% Phe:
0
7
0
0
0
0
0
7
0
0
0
0
7
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
7
0
0
7
0
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
14
7
0
0
14
0
0
0
0
0
% I
% Lys:
0
0
0
7
0
7
14
27
0
7
7
0
7
7
54
% K
% Leu:
0
0
0
0
0
7
0
0
7
7
0
14
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% M
% Asn:
0
0
0
27
0
0
27
0
0
0
0
0
0
0
0
% N
% Pro:
0
74
0
7
7
0
0
7
0
34
60
7
47
34
7
% P
% Gln:
0
0
7
0
7
0
0
0
7
0
7
0
0
27
7
% Q
% Arg:
0
0
0
0
0
0
14
0
0
0
0
0
0
7
7
% R
% Ser:
0
0
7
7
0
7
7
7
7
0
7
0
14
0
0
% S
% Thr:
0
0
7
7
0
7
0
34
14
14
7
0
7
0
0
% T
% Val:
0
7
0
0
7
0
0
7
14
7
0
60
0
0
0
% V
% Trp:
0
0
0
0
0
60
0
0
0
0
0
0
0
0
0
% W
% Tyr:
80
0
0
0
0
0
0
7
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _